Manuka honey possesses strong anti-cancer properties as many research had found what a small teaspoon of Manuka honey can do.
According to various studies and research findings, there is evidence suggesting that Manuka honey exhibits potential anti-cancer activity. It is closely linked to oxidative stress, chronic inflammation, and cancer. The flavonoids and phenolic acids present in Manuka honey contribute to its anti-cancer properties.
Here are some key findings related to Manuka honey’s impact on cancer:
- Protection against DNA damage: Manuka honey has been found to protect DNA from oxidative damage.
- Mediating oxidative stress and inflammation: Manuka honey can help mediate oxidative stress and inflammation associated with cancer.
- Reduced resistance to apoptosis: Manuka honey has been shown to reduce resistance to apoptosis (programmed cell death) in cancer stem-like cells.
- Enhanced chemopreventive effects: Manuka honey enhances the effectiveness of the chemotherapy drug 5-fluorouracil on colon cancer cells.
- Inhibitory effects on cellular growth: Manuka honey inhibits the growth of cancer cells and shows promise as a preventive or curative food therapy for colon cancer.
- Selective antagonism of IL-6 receptor pathway: Manuka honey selectively antagonizes the IL-6 receptor pathway, highlighting its potential as an anti-tumor agent.
- Induction of cell death: Manuka honey induces cell death in various cancer cells by enhancing oxidative stress, regulating energy metabolism, and suppressing metastatic ability.
- Effects on tumour microenvironment: Honey, including Manuka honey, can alter the tumour microenvironment, reduce angiogenesis, and modulate immune cells to be more hostile towards cancer cells.
- Sensitization to tumour drugs: Manuka honey enhances the sensitivity of certain cancer cells to tumour drugs such as Doxorubicin.
- Inhibitory effects on breast cancer: Australian/New Zealand Manuka honey has shown inhibitory effects on breast cancer in animal studies.
- Reduction of colorectal cancer stem cell volume: Manuka honey reduces the volume of colorectal cancer stem cell cultures and affects their self-renewal ability.
- Reduction of metastatic properties: Honey, especially Manuka honey, can reduce the metastatic properties of prostate cancer cells by promoting loss of adhesion.
These findings suggest that Manuka honey holds promise as a potential chemo-preventive and adjunct therapy for certain types of cancer.
Further studies will be shared here on how effective is Manuka honey against cancer.
REFERENCE:
https://pubmed.ncbi.nlm.nih.gov/30639116/
https://pubmed.ncbi.nlm.nih.gov/34883427/
https://pubmed.ncbi.nlm.nih.gov/32387951/
https://deainfo.nci.nih.gov/advisory/CTAC/1121/Dueck.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865795/
https://www.sciencedirect.com/science/article/abs/pii/S030881462301302X